PFKP antibody

Catalog No. ABIN2728759

The Mouse Monoclonal anti-PFKP antibody has been validated for WB, IHC, IF and FACS. It is suitable to detect PFKP in samples from Human.

Quick Overview for PFKP antibody (ABIN2728759)

Target: PFKP (phosphofructokinase, Platelet (PFKP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PFKP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 1A11

Product Details anti-PFKP Antibody

Characteristics: Homo sapiens phosphofructokinase, platelet (PFKP), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human PFKP(NP_002618) produced in HEK293T cell.

Isotype: IgG1

Application Details

Application Notes: WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for PFKP

Target: PFKP (phosphofructokinase, Platelet (PFKP))

Alternative Name: PFKP

Background: The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM, MIM 610681) and liver (PFKL, MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.

Molecular Weight: 85.4 kDa

Gene ID: 5214

NCBI Accession: NM_002627

HGNC: 5214

Pathways: Warburg Effect